Public Perceptions About the Concept of Medication Reuse

existence Perceptions About the Concept of Medication ReuseMedication drops The public perceptions more or less the concept of music reuseChapter star1. Introduction1.1 Background, definitions, and classification of medical copsThere is a growing environmental realisation in the last few years, it is recognis suitable that the worlds environmental carbon emissions, and globose warming problems are increasing. Mevery organisations work to apply green principles of health care programs in their way for going green (Xie, 2012).In the UK, the Centre for sustainable Healthcare (CSH) the institution which was developed in 2008 to help NHS stifle carbon liberations and emissions by 80% by 2050 by involving health care professionals, patients, and the society clarifying the connections between environment and health care system (Stancliffe, 2014). tout is defined by European Union Waste Framework Directive (2008), as any substance or object which the holder discards or intends or is required to discard.All excesss created by medical activities f alones under health care depopulates. The lofty College of Nursing (RCN) report and the World Health Organisation (WHO) described health care wastes as all wastes produced by research facilities, laboratories, and organisations providing health and social care. More everywhere, it involves the waste originating from short or sprinkled founts such as that generated in the health course and social care started at home such as dialysis, insulin injections, bandages, swabs, sharps, blood, medications and incontinence pads (RCN, 2014 and WHO, 2011). among (80) % of the waste produced by health-care providers is considered non-risk or general health-care waste, while the remaining (20) % of healthcare waste is considered as hazardous that maybe may be infectious, toxic or radioactive and may create a diversity of health risks. Health-care waste consists of possibly dangerous microorganisms with potential infectious risks such as development of microorganisms rebarbative to medication from health-care institution into the environment, and can infect patients, healthcare suppliers and the public. WHO classified the hazardous health care waste into (Appendix 1) infectious waste, pathological waste, sharps waste, pharmaceutical waste, ge nonoxic waste, chemical waste, level-headed metals wastes and the radioactive waste. Pharmaceutical waste is waste containing pharmaceutical that are expired, or no longer employ items polluted by or including pharmaceuticals (WHO, 2011).Usually not all the medications dispensed to the patients w convalescent be used, this is mainly due to many factors such as adverse drug reaction intolerance, relief of symptoms, changing the dose/dosage forms, medicine non-compliance and/or non-adherence issues and medicine being expired (Dharmender, 2013).Pharmaceutical waste is defined by UK Department of health (2013), as expired, tonic, spilt, and contaminated medicativ e products, drugs, vaccines and sera that are no longer required and need to be dispose of appropriately and/ or discarded items contaminated with medicinal, such as bottles or boxes with residues, gloves, masks, connecting tubing, spray bodies and drug vials.Abou-auda HS (2003), defined medication wastage as any medication or drug product that had been dispensed by a prescription or deal over the counter (OTC) which is not honesty consumed.Chapter two2. Literature review2.1 causes of medication wastageDrugs are wasted when dispensed to patients who are not taken them. In order to minimise the wastage of medications, it is important to investigate the causes behind medicines being returned, impudent, and wasted by the patients. A review of the possible factors evidenced to potentially cause medication waste was conducted to summarise the most important causes of medicine returned unused.2.1.1 Patient terminalMedications being returned unused by the patients resulting from pati ent death was reported in sestet studies. Mackridge et al. (2007), a ford sectional plain of returned medicines to fifty wizard confederacy pharmacies and forty two general practitioner surgeries in Eastern Birmingham (UK) over eightsome weeks, Cameron (1996), a self-reporting questionnaire study in 58 community pharmacies in Alberta (Canada) over eight weeks, and Ekedahl (2006), a spread over sectional study include fifty nightclub community pharmacies in Sweden reported that patient death was the most jet cause of medication waste.In the study by Langley et al. (2005), a small cross sectional observational study in eight community pharmacies and five general practitioner surgeries in East Birmingham/UK over foursome weeks, patient death was the second most common cause of returned unused medicines by the patients.Data from Cook A (1996), a cross sectional study of returned medicines to seventeen community pharmacies over one month in UK, Hawksworth et al. (1996), a cross sectional study of returned medicines included 30 community pharmacies in UK, Coma et al. (2008), a cross sectional study of returned medicines to 38 community pharmacies over three months showed that patient death was reported but accounted only for about quarter of all returned unused medicines.2.1.2 Medication changed or discontinuedThere is a proof in the literature that changing medications is a considerable cause of medication returned unused by the patients, it is reported as a common cause of medication waste (Cameron 1996, Cook 1996, Hawksworth et al. 1996, Morgan 2001, Daniszewsi et al.2002, Langley et al. 2005, Abahussain et al. 2006, Ekedahl 2006, Mackridge et al. 2007, Braund et al. 2008, Coma et al. 2008, Braund and Gn et al. 2009, Braund and Peake et al. 2009, James et al. 2009).Data from (Hawksworth et al. 1996, Daniszewsi et al.2002, Langley et al. 2005, Abahussain et al. 2006, Braund et al. 2008), found that changing medications was the most common reported cause of medication being wasted.2.1.3 Medication Expired2.2 The environmental impact of unused wasted returned medicationsThe toxic ecological cause of the pharmaceutical aim in the environment was studied and evaluated in the last few years. Data from Heberer (2002) and Woodhouse (2003), confirm the presence of pharmaceuticals in water and considered it serious, as it is not aggregately remote and even if it is present in trace levels is still considered pollutant to water receivers. The improper household disposal practices of unused medicines, via the local waste, the sewers, and the toilet was identified, as a source of water contamination (Bound, 2006).The effect of pharmaceutical wastes in the environment was linked to possible development of endocrine deactivating compounds, reducing fertility, and antibiotic resistance bacteria. Data from Schwartz et al. (2003), substantiate the development of bacterial resistance as vancomycin resistant enterococci and beta-lactam-hydrolys ing Enterobacteriaceae were cultivated from all wastewater biofilms. In the study by Lange et al. (2001), the feminising effects of endocrine-disrupting compounds, such as ethinyl estradiol, the synthetic hormone used in the contraceptive pill, on fish near wastewater treatment works outfalls was measured.2.3 The economic impact of unused wasted returned medicineStudies from inside (five) and outside (six) UK, estimated the value of the cost of medication waste are reviewed below.Results from Hawksworth et al. (1996), a cross sectional study included thirty community pharmacies in Kirklees/West Yorkshire (UK) over a period of one month showed an estimated cost of 37 trillion of unused medicine were from patients home.Langley et al. (2005), a small cross sectional observational study in eight community pharmacies and five general practitioner surgeries in East Birmingham/UK over four weeks, showed that the fundamental cost of returned medicines was 3986 and 3751 respectively.In the study by Mackridge et al. (2007), a cross sectional study reported an estimate of 75 million value of returned medicines to fifty one community pharmacies and forty two general practitioner surgeries in Eastern Birmingham over eight weeks. In the same year, the UK National Audit Office report, proposed that apiece year an estimate of 100 million value of unused returned medicine. As the 100 million estimate was establish on unused medicine that truly returned, this was considered as an underrated figure of the full cost of wasted medicines, as a result the department of health estimated that as much as 10% of all drugs prescribed were wasted (10% of the NHS prescribing budget) which is estimated to be 800 million-worth of drugs are wasted yearlyly in primary care.Data from Trueman et al. (2010), a research undertaken by the York Health Economics pond and London School of Pharmacy in 2009, estimated that the yearly cost of the primary and community care medicines wastage in UK NH S was around 300 million per year ( 250-300 million per year), with estimated 90 million of unused medicines stored in individuals homes, 110 million returned to community pharmacies over the course of a year, and up to 50 million of NHS supplied medicines that are disposed of annually by care homes. The authors of this report also estimated that less than 50% of this total figure is cost effectively preventable.International studies from outside UK was also included and reviewed. A Canadian study by Cameron S (1996), in fifty eight pharmacies over eight weeks estimated the cost of unused medicines returned was $60350, the extrapolated cost which included the whole 750 community pharmacies in Alberta during the same eight weeks period was $716400.Coma et al. (2008), a cross sectional study included thirty eight community pharmacies in Barcelona/Spain over a period of three months, showed that the estimated cost of returned medicines was 8,539.9, the extrapolated cost for the 20,461 community pharmacies in whole Spain was a round 129 million.Although the reuse concept of patients unused returned medicines is considered unethical in the fall in Kingdome (UK), the unused medicines are returned in large quantities and sire important financial value, with the preponderance considered acceptable to be used again by another patient (Mackridge, 2007).Table 1. Summary of research studies evaluating the economic impact of wasted medicineStudyStudy setting and lengthStudy methodCountryMain FindingsHawksworth et al. (1996)30 CPs over duration of 1 monthCross sectional questionnaireUKA total of 1,091 items were returned by 366 patients with estimated value of 37 millionLangley et al. (2005)8 CP and 5 GPs over duration of 4 weeksCross sectional observational studyUKA total of 340 items were returned (42 to GPs and 298 to CPs). The total cost of returned items was 3986 to GPs and 3751 CPs.Mackridge et al. (2007)51 CPs and 42 GPsover duration of 8 weeksCross sectional stud yUKA total of 3765 itemswere returned by 910 patients with estimated value of 75 millionUK National Audit Office report (2007)Based on old analysis conducted by department of healthBased on previous analysis conducted by department of healthUKProposed that each year an estimate of 100 million value of unused returned medicine.Trueman et al. (2010)403 of the 466 items identified in the public thought were able to be priced. Costs were identified /item using British National Formulary (BNF).Public surveyUKEstimated that the annual cost of the primary and community care medicines wastage in UK NHS was around 300 million per year ( 250-300 million per year).Cameron S (1996)58 CPs in Alberta (8% of provincial total)over duration of 8 weeksSelf-reporting questionnaireCanadaThe estimated cost of the unused medicines returned was $60350. The extrapolated cost for 750 CPs is in Alberta during the same 8 week period was $716400.Morgan (2001)Sample of 73 of Hampshire retirement community cit izens aged 65 years or older.over duration of 7 monthscross-sectional pilot survey/ QuestionnaireUSThe total cost of 2078 wasted pills was US $ 2,011.00 with mean annual cost of wasted medication was $30.47/person (range = $0-$131.56).Individual costs were modest, but if $30/individual demonstrate a low estimate of average annual cost of waste, the US extrapolated cost was estimated to be not less than $1 billion per year.Abou-auda (2003)A total of 1641 households participated (1554 from Saudi Arabia, 87 from other countries)Questionnaire /Pilot studySaudi Arabia, and capital cities of Kuwait, Oman, Qatar, and United Arab Emirates U.A.EThe estimated cost of unused medicines by families in Saudi Arabia capital cities of Kuwait, Oman, Qatar, and United Arab Emirates (U.A.E) was $150 million.Coma et al. (2008)38 CPs over duration of 3 monthsCross sectional questionnaireSpainThe estimated cost of returned medicines was 8,539.9. The extrapolated cost for the 20,461 CPs in whole Spain was 129.6 millionEl-Hamamsy (2011)20 CPs over duration of 1 monthQuestionnaire(Closed-ended questions used only)Cairo/EgyptThe total wholesale price of returneddrugs calculated at10988.84 Egyptian pounds (around $1962.32 US)Hassali et al. (2012)Two parts1) Medicine wastage in the patients home.2) Medicine wastage by the benefactor at the pharmacy desk.over duration of 6 monthsA descriptive study of two parts1) Prospective randomised community based trial.2) Wasted medicines were collected from the patients who pass back the unwanted medicines to the pharmacy desk in the Hospital.MalaysiaThe total cost of the returned medications within 6 months was MYR 59,566.50 (Malaysian ringgit) with a monthly average of about MYR 9,927.75. the extrapolated cost for one year of the medications returned was MYR 119,133.00Information from medication waste campaign website illustrated that the estimated cost of unused medication (300 million/year) could pay (by the average cost) for 11,778 more communi ty nurses, 19,799 more drug treatment courses for breast cancer, 101,351 more knee replacements, 80,906 more hip replacements, and 300,000 more drug treatment courses for Alzheimers. In 2012 the NHS of Berkshire started major actions to reduce medicine waste, data from the NHS south central press release, showed that an estimate cost of wasted medicine across the Berkshire NHS and south central was 20 million per year.The full cost of wasted medicine is not only the cost of returned medicines as estimated by the studies reviewed above (Table 1), in addition the cost of the destroying processes of the returned medicines, and the hidden costs of non-compliance/non-adherence effects which was not studied should be added to the full cost of wasted medicines in future research (UK National Audit Office Report, 2007).2.4 Disposal practices for unused medications2.5 Public perceptions about unused/wasted pharmaceuticals2.6 Medication reuse and recyclingA medicine reuse concept involves the return of unused and/or sealed medicines to a pharmacy, healthcare facility or charitable organisation for subsequent redistribution to recipients locally or internationally. This was implemented on a charitable basis in the United States of America (USA) and in developing countries which experienced poor medicine supply (Bero, 2010).Although such practice is considered unethical and not approved in UK, it may have environmental and economic advantages as many of these considered acceptable to be used again (Mackridge, 2007).Ipsos MORI conducted 1,101 face to face interviews for Sustainable Development Unit of the UK NHS (SDU) with respondents aged fifteen and more using around one hundred and fifty sample points. The research was carried out in two periods between the eleven of November and the fifth of celestial latitude 2011. All data was weighed to reverberate the population profile of British people aged fifteen and more. Data from this recent survey reported that around half (prenominal) of the British people (52%) agreed to accept reissued medicines returned (that are unused and the safety was checked) by other patients while 32% said that they would not.According to Dr David Pencheon the director of sustainability unit, medicine reuse concept had been unaccepted in the past based on the assumption that patients are not willing to take the medicine returned by others. In healthcare system, the health care provider is always deviate strongly on the side of safety caution and discard medicines. For the time beings, the economics of this demeanour need to be reconsidered (Cooper, 2012).Chapter ThreeResearch planEcologicalImpactIs medicine being wastedNoYesNoImagine that Mr. Smith who is ill with diabetes is prescribed four medications each month. He doesnt pay for his medicines. He use all medicines as prescribed.Imagine that Mr. Smith who is ill with diabetes is prescribed four medications each month. He doesnt pay for his medicines. He sometimes fails to take his medicines as prescribed.YesAppendicesAppendix 1 (WHO and RCN Definitions and classifications of health care wastesInfectious wasteWaste contaminated by blood and its secondary products, cultures and supplies of infectious agents, waste come from isolated patients, any infected thrown away diagnostic samples with blood and remains fluids, infected animals from laboratories, and contaminated swabs, bandages, and equipment such as disposable medical devices.Pathological wasteRecognizable parts of the body and contaminated animal dead bodies.Genotoxic wasteVery dangerous, mutagenic, teratogenic, and carcinogenic, such as cytotoxic drugs and their metabolites.Pharmaceutical wasteExpired, unused, and contaminated drugs vaccines and seraRadioactive wasteSuch as contaminated glass materials with radioactive diagnostic or therapeutic materials.Heavy metals wasteSuch as broken mercury thermometers.ChemicalsSuch as broken mercury thermometersSharpsSuch as syringes, needles, dispo sable scalpels and bladesHazardous or Non Hazardous wasteclinical waste if it contains or is contaminatedwith a medicine containing eitherA pharmaceutically-active substance (a substance able to affect biological systems) orA dangerous substance such as chemicals at sufficient concentration to produce a hazardous property.Clinical or Non Clinical wasteHazardous if it contains or is contaminated with a cytotoxic or cytostatic medicine. Other medicines are not hazardous waste.Offensive waste or sometimes called hygiene waste)Is waste that is non-infectious and not clinical, but may cause offence due to the presence of recognisable health care waste materials, body fluids or odour, and secretions or excretions or that collection and disposal is not subject to special requirements in order to prevent infection.*Adapted from WHO fact planing machine (2011), and RCN guidance (2014)